SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS AND CARDIOVASCULAR EVENT PROTECTIONS: HOW APPLICABLE ARE CLINICAL TRIALS AND OBSERVATIONAL STUDIES TO REAL-WORLD PATIENTS?

Sodium glucose co-transporter 2 inhibitors and cardiovascular event protections: how applicable are clinical trials and observational studies to real-world patients?

Objective This study evaluated the characteristics of new users of sodium glucose co-transporter 2 inhibitors (SGLT2i) in clinical practice to assess the applicability of the findings from clinical trials (Empagliflozin, Cardiovascular Outcomes and Mortality in Type 2 Diabetes (EMPA-REG OUTCOME) trial, Dapagliflozin Effect on Cardiovascular Events

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Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates

Abstract Tunicates are evolutionary model organisms bridging the gap between vertebrates and invertebrates.A genomic sequence in Ciona intestinalis (CiOX) shows high similarity to vertebrate orexin receptors and protostome allatotropin here receptors (ATR).Here, molecular phylogeny suggested that CiOX is divergent from ATRs and human orexin recepto

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Peripheral-Free Calibration Method for Redundant IMUs Based on Array-Based Consumer-Grade MEMS Information Fusion

The MEMS array-based inertial navigation module (M-IMU) reduces the measurement singularities of MEMS sensors by fusing multiple data processing to improve its navigation performance.However, there are still existing random and fixed errors in M-IMU navigation.The calibration method calibrates the fixed error parameters of M-IMU to further improve

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Groundwater recharge potentiality mapping for opportune augmentation following two MCDMs for a Western Himalayan watershed

Abstract Accounting potential zones for recharging groundwater is a prerequisite before the implementation of the springshed conservation program.Many studies have suggested that the resurgence of the springs in the Himalayan region is waning due to anthropogenic and Climate Change impacts.Typical physical methods of ut solution gel for cats rechar

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